Impaired Postprandial Metabolism of Apolipoprotein B48-Containing Remnant Particles in Normolipidemic Subjects With Brittle Type 1 Diabetes
نویسندگان
چکیده
منابع مشابه
Isolation and characterization of apolipoprotein B48-containing lipoproteins with a monoclonal antibody against apolipoprotein B48.
AIM Remnant lipoproteins are well known to play a pivotal role in atherosclerosis. In patients with postprandial dyslipidemia, metabolic pathways for exogenous lipoproteins are generally disturbed, resulting in accumulation of chylomicron remnants. Although it has been difficult to make a specific antibody against apolipoprotein B48 (apoB48) , a constituent of exogenous lipoproteins, we succeed...
متن کاملprevalence of atopic dermatitis in children with type 1 diabetes mellitus in southeastern of iran (kerman province): a case-control study
چکیده ندارد.
15 صفحه اولPostprandial enrichment of remnant lipoproteins with apoC-I in healthy normolipidemic men with early asymptomatic atherosclerosis.
OBJECTIVES Recently, we reported that exaggerated postprandial triglyceridemia in normolipidemic patients with coronary artery disease is associated with enrichment of remnant lipoproteins with apolipoprotein C-I (apoC-I). In this study, the number and composition of chylomicron remnants and very low density lipoproteins (VLDLs) were examined in 30 asymptomatic normolipidemic 50-year-old men wi...
متن کاملEvidence of increased secretion of apolipoprotein B-48-containing lipoproteins in subjects with type 2 diabetes.
Patients with type 2 diabetes have high levels of triglyceride-rich lipoproteins (TRLs), including apolipoprotein B-48 (apoB-48)-containing TRLs of intestinal origin, but the mechanism leading to overaccumulation of these lipoproteins remains to be fully elucidated. Therefore, the objective of this study was to examine the in vivo kinetics of TRL apoB-48 and VLDL, intermediate density lipoprote...
متن کاملDistribution of apolipoprotein ai-containing lipoprotein subclasses in plasma of normolipidemic subjects.
The distribution of apoA-I among apoA-I-containing lipoprotein (AI-Lp) subclasses in plasma was studied by immunoblotting utilizing agarose gel matrix incorporating anti-apoA-I as the transfer medium. Nine AI-Lp subclasses were detected in the plasma of normolipidemics, with relative molecular masses ranging from 70,000 to ≥ 354,000 and diameters from 7.12 to ≥ 11.6 nm. The mass distribution of...
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ژورنال
عنوان ژورنال: Diabetes Care
سال: 2009
ISSN: 0149-5992,1935-5548
DOI: 10.2337/dc08-1573